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Filtered Search Results
TARGETMOL CHEMICALS INC VICRIVIROC MALEATE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1. purity: 97%
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Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML
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Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic. It acts as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is utilized in research for conditions such as schizophrenia and bipolar disorder.
- Antagonist of serotonin, adrenoceptors, dopamine, and histamine receptors.
- Brain-penetrant atypical antipsychotic.
- Used in schizophrenia and bipolar disorder research.
- Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B and D3 receptors relative to D2.
- May offer superior therapeutic effects on anxiety.
- Demonstrates anxiolytic-like effects in animal models.
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g·mol-1 | C18H24N2O4 | 10 MG
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Cipralisant maleate is a research-grade histamine H3 receptor antagonist supplied as the maleate salt. It is used in pharmacology and neuroscience studies to probe H3 receptor activity and related signaling pathways. Provided as a solid with high reported purity, this compound is for laboratory research use only and not for human or veterinary applications.
- Orally active histamine H3 receptor antagonist for research applications.
- High purity (99.8%).
- White to off-white solid appearance.
- Soluble in DMSO (≥ 100 mg/mL).
- Molecular weight 332.39 g·mol-1; formula C18H24N2O4.
- Stable as powder at -20°C for long-term storage; in solution store at -80°C.
- Supplied in small laboratory-scale quantities suitable for preclinical studies.
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Selleck Chemical LLC Perhexiline maleate
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Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 M and 148 M for rat heart CPT1 and liver CPT1 respectively and also inhibits carnitine palmitoyltransferase 2 (CPT2)
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eMolecules 1785665-61-3 | Medchem Express | VUF11207 (fumarate) | 5mg | 515743918 | HY-110318 | MFCD27991278 | 586.657 | C31H39FN2O8
ChemScene | Methyl 4-amino-35-dichloro-2-fluorobenzoate | 100mg | 746310752 | CS-0612352 | 2649788-83-8 | 238.040 | C8H6Cl2FNO2
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Medchemexpress LLC Betrixaban maleate | 936539-80-9 | MFCD16038040 | 99.8% | 567.98 | C27H26ClN5O7 | 10 MG
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Betrixaban maleate is the maleate salt of betrixaban, a potent and selective orally efficacious factor Xa (fXa) inhibitor with an IC50 of 1.5 nM. Supplied as a solid for research use, it demonstrates antithrombotic activity and includes specified purity, storage, and solubility data for laboratory handling.
- High purity (99.8%).
- White to off-white solid form.
- Molecular weight 567.98 g/mol.
- CAS number 936539-80-9.
- Soluble in DMSO (50 mg/mL) and in water (2 mg/mL) with warming and sonication.
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Provided as a 10 MG research pack.
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Medchemexpress LLC Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenylethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) | 599179-03-0 | 99.9% | 649.70 | 25 MG
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Vicriviroc maleate is a potent, selective, oral bioavailable, and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM. It also inhibits HIV-1 in PBMC cells. This product is for research use only and not sold to patients.
- Potent and selective CCR5 antagonist
- Oral bioavailable and CNS penetrating
- Inhibits HIV-1 in PBMC cells
- Available as a white to light yellow solid
- Ships at room temperature in continental US
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eMolecules 18162-82-8 | Chloromethyltriisopropoxysilane | Ambeed | MFCD05664343 | 254.830 | C10H23ClO3Si | 96.000 | CC(C)O[Si](CCl)(OC(C)C)OC(C)C | 1g | 521471713
Chloromethyltriisopropoxysilane | Ambeed | 18162-82-8 | MFCD05664343 | 254.830 | C10H23ClO3Si | 96.000 | CC(C)O[Si](CCl)(OC(C)C)OC(C)C | 1g | 521471713
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eMolecules 130561-48-7 | AstaTech | 3-CINNOLINECARBOXYLIC ACID 1-(4-CHLOROPHENYL)-14-DIHYDRO-5-(2-METHOXYETHOXY)-4-OXO- | 0.25g | 448268141 | A12000 | 95 | MFCD28556890 | 374.78 | C18H15ClN2O5
Pharmablock | 6-methoxy-5-nitro-1H-indazole | 25mg | 788496058 | PBDW003 | 152626-75-0 | MFCD11007881 | 193.162 | C8H7N3O3
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Pfaltz & Bauer DIMETHYL MALEATE 99% 250G
Dimethyl maleate 99%; 250G CAS# 624-48-6
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Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MG
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Asenapine maleate, also known by its synonym Org 5222 maleate, is a brain-penetrant atypical antipsychotic. It acts as an antagonist for various receptors, including serotonin, adrenoceptors, dopamine, and histamine receptors. It is investigated for its potential in treating schizophrenia and bipolar disorder.
- Acts as an antagonist of serotonin receptors.
- Exhibits antagonism towards adrenoceptors.
- Functions as a dopamine receptor antagonist.
- Blocks histamine receptors.
- Investigated for its use in schizophrenia.
- Studied for application in bipolar disorder.
- May offer superior therapeutic effects on anxiety symptoms.
- Demonstrates anxiolytic-like effects in behavioral tests in mice.
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Medchemexpress LLC AZD9496 | 1639042-08-2 | 10 MG
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AZD9496 is an orally active, selective estrogen receptor degrader (SERD) and an effective, selective estrogen receptor (ERα) antagonist. It demonstrates high potency with an IC50 of 0.28 nM for ERα antagonism and significantly inhibits MCF-7 cell growth.
- Orally active, selective estrogen receptor degrader (SERD)
- Effective and selective estrogen receptor (ERα) antagonist
- IC50 of 0.28 nM for ERα antagonism
- Inhibits MCF-7 cell growth with an EC50 of 0.04 nM
- High selectivity over other nuclear hormone receptors
- Shows significant tumor growth inhibition in estrogen-dependent MCF-7 xenograft models
- Leads to further growth-inhibitory effects when combined with PI3K pathway and CDK4/6 inhibitors
- Demonstrates significant activity in long-term estrogen-deprived models
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Medchemexpress LLC NB-598 (maleate) | 155294-62-5 | MFCD22665748 | 99.4% | 565.74 | C31H35NO5S2 | 10 MG
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NB-598 maleate is a research-grade small molecule that acts as a potent, competitive inhibitor of squalene epoxidase (SE). It is used in biochemical and cell-based studies to suppress triglyceride and sterol biosynthesis via the farnesol pathway and is supplied as the maleate salt in solid form or as a concentrated DMSO solution for assay use.
- Potent competitive inhibitor of squalene epoxidase.
- Used to suppress triglyceride and cholesterol biosynthesis in biochemical studies.
- Supplied as the maleate salt for improved stability and handling.
- Available as small solid quantities and as a 10 mM solution in DMSO for convenience in assays.
- High reported purity (~99.4%) suitable for research applications.
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TARGETMOL CHEMICALS INC --DIZOCILPINE MALEATE 50MG
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Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. purity: 99%
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Medchemexpress LLC Pd-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 1 ML
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PD-168077 maleate is a selective dopamine D4 receptor agonist with a Ki of 9 nM. It is intended for research use only. It exhibits intrinsic activity at the D4 receptor, leading to quinpirole-like inhibition of forskolin-stimulated cAMP accumulation or stimulation of [3H]thymidine uptake.
- Shows >100-fold selectivity over other D2-like receptor family members and D1-like counterparts.
- Demonstrates 20-fold selectivity over α1 and α2 receptors.
- Exhibits 45-fold selectivity over 5-HT1A.
- Shows 460-fold selectivity over 5-HT2A receptors.
- Induces synaptic translocation of Ca2+/calmodulin-dependent protein kinase II in cultured prefrontal cortical neurons.
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